Temperature mapping in mixed tissue types
Megan Poorman1, Ieva Braškutė2, Lambertus W Bartels2, William A Grissom1
Relatively stable V1
MRI thermometry enables non-invasive real-time temperature monitoring of thermal therapies, such as tumor ablation. The typical method used for thermometry quantifies the proton resonant frequency (PRF) shift with temperature, which becomes inaccurate in fatty tissues. This can cause major problems for guiding therapies in organs such as the breast and liver. This code repository implements an algorithm that can perform accurate PRF-shift thermometry in tissues containing up to 90% fat and also correct errors due to motion, respiration, and scanner drift, in a real-time compatible manner. A numerical phantom simulator is provided as a demo for the algorithm.
1Vanderbilt University, USA
2University Medical Center Utrecht, Netherlands