Open Source framework for the development and hardware-independent execution of MR pulse sequences for imaging and spectroscopy. MRI sequences can be programmed in MATLAB and executed on real hardware.


Kelvin Layton1, Stefan Kroboth1, Jochen Leupold1, Huijun Yu1, Feng Jia1, Jon-Fredrik Nielsen2, Sebastian Littin1, Tony Stöcker3, Maxim Zaitsev1

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Stable release, MIT License

Pulseq is an open source framework for the development, representation and execution of magnetic resonance (MR) sequences. A central contribution of this project is an open file format to compactly describe MR sequences suitable for execution on an MRI scanner or NMR spectrometer. MATLAB and C++ source code is provided for reading and writing sequence files.

Currently, Pulseq sequences can be executed on the following platforms. Please contact us if you would like to run open and flexible sequences at your institution.

  • Siemens
  • GE
  • Bruker



1Medical Physics, University Medical Center Freiburg, Germany

2Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA

3German Center for Neurodegenerative Diseases, Bonn, Germany


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